Background: An adverse hematological interaction between vitamins E and
K has been reported, primarily in patients on anticoagulants. However, little is
known regarding circulating levels or tissue concentrations of vitamin K in response
to vitamin E supplementation. The purpose of this study was to examine the effect of
different levels ... read moreof dietary α-tocopherol on phylloquinone and menaquinone-4
concentrations, while maintaining a constant intake of phylloquinone, in rat
tissues.
Keywords: high performance liquid chromatography,
menaquinone-4.
Tovar, Alison, Clement K. Ameho, Jeffrey B. Blumberg, James W.
Peterson, Donald Smith, and Sarah L. Booth. "Extrahepatic tissue concentrations of
vitamin K are lower in rats fed a high vitamin E diet." Nutrition & Metabolism 3,
no. 1 (12, 2006): 1-6.