%0 PDF %T Extrahepatic tissue concentrations of vitamin K are lower in rats fed a high vitamin E diet. %A Tovar, Alison.; Ameho, Clement K.; Blumberg, Jeffrey B.; Peterson, James W.; Smith, Donald.; Booth, Sarah L. %D 2016-08-16T18:23:35.595Z %8 2016-08-16 %R http://localhost/files/rn301c633 %X Background: An adverse hematological interaction between vitamins E and K has been reported, primarily in patients on anticoagulants. However, little is known regarding circulating levels or tissue concentrations of vitamin K in response to vitamin E supplementation. The purpose of this study was to examine the effect of different levels of dietary α-tocopherol on phylloquinone and menaquinone-4 concentrations, while maintaining a constant intake of phylloquinone, in rat tissues.; Keywords: high performance liquid chromatography, menaquinone-4.; Springer Open. %[ 2018-10-11 %9 Text %~ Tufts Digital Library %W Institution