Cranial Irradiation for Pediatric T-lineage Acute Lymphoblastic Leukemia: A Systematic Review.

Kelly, Michael.


  • Abstract: Pediatric cooperative groups have heterogeneous approaches to cranial irradiation therapy (CRT) for T-lineage acute lymphoblastic leukemia (T-ALL). We performed a systematic review of studies that specified a radiation strategy and reported survival for pediatric T-ALL. Our analysis included 59 publications reporting 75 treatment groups (patient n=5731). Over time, average event-free ... read more
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