Computational Prediction of Functional Abortive RNA in E. coli.

Marcus, Jeremy I.

Failure by RNA polymerase to break contacts with promoter DNA results in release of bound RNA and re-initiation of transcription. These abortive RNA were assumed to be non-functional but have recently been shown to affect termination in bacteriophage T7. Little is known about the functional role of these RNA in other genetic models. Using a computational approach, we investigated whether abortive ... read more

This object is in collection:
Undergraduate Honors Theses
Computational biology.
Non-coding RNA.
Genetic regulation.
Gene expression.
Escherichia coli--Genetics.
Tufts University. Department of Computer Science.
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ID: tufts:sd.0000396
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