Endogenous Two-Photon Excited Fluorescence Imaging Characterizes Neuron and Astrocyte Metabolic Responses to Manganese Toxicity.

Stuntz, Emily.
Gong, Yusi.
Sood, Disha.
Liaudanskaya, Volha.
Pouli, Dimitra.
Quinn, Kyle P.
Alonzo, Carlo Amadeo.
Liu, Zhiyi.
Kaplan, David, 1953-
Georgakoudi, Irene.
2017.

As neurodegenerative conditions are increasingly linked to mitochondrial dysfunction, methods for studying brain cell metabolism at high spatial resolution are needed to elucidate neurodegeneration mechanisms. Two-photon excited fluorescence (TPEF) imaging is a non-destructive, high-resolution technique for studying cell metabolism via endogenous fluorescence of reduced nicotinamide adenine dinucl... read more

Subjects
Nervous system--Degeneration.
Tufts University. Department of Biomedical Engineering.
Permanent URL
http://hdl.handle.net/10427/012429
Original publication
Stuntz, Emily, Yusi Gong, Disha Sood, Volha Liaudanskaya, Dimitra Pouli, Kyle P. Quinn, Carlo Alonzo, Zhiyi Liu, David L. Kaplan, and Irene Georgakoudi. "Endogenous Two-Photon Excited Fluorescence Imaging Characterizes Neuron and Astrocyte Metabolic Responses to Manganese Toxicity." Scientific Reports 7, no. 1 (April 21, 2017). doi:10.1038/s41598-017-01015-9.
ID: tufts:22344
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