Description |
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Background: Stromal-epithelial interactions mediate breast development,
and the initiation and progression of breast cancer. In the present study, we
developed 3-dimensional (3D) in vitro models to study breast cancer tissue
organization and the role of the microenvironment in phenotypic
determination.
Keywords: 3 Dimensional, ... read moreDulbecco's modified Eagle's medium,
extracellular matrix, Fetal bovine serum, human breast cancer cell line, matrix
metalloproteinase 3, reconstituted basement membrane, reduction mammoplasty
fibroblasts, transmission electron microscopy.
Springer Open.read less
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Citation |
- Krause, Silva, Maricel V. Maffini, Ana M. Soto, and Carlos
Sonnenschein. "The microenvironment determines the breast cancer cells' phenotype:
organization of MCF7 cells in 3D cultures." BMC Cancer 10, no. 1 (12, 2010):
1-13.
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