Intergenerational Effects of Paternal B vitamin Intake on DNA Methylation, Gene Expression, and Intestinal Tumorigenesis in the Apc1638N Mouse Model of Colorectal Cancer.

Sabet, Julia.


  • Abstract: Background: Evidence is emerging that paternal diet influences various aspects of offspring health, although the underlying mechanisms are unclear and studies of the effects of paternal diet on offspring risk of cancer are lacking. We aim to investigate the extent to which diet-induced DNA methylation patterns are transmitted from father to offspring and whether paternal diet alters ... read more
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