Selection Finder (SelFi): A computational metabolic engineering tool to enable directed evolution of enzymes.

Hassanpour, Neda.

Ullah, Ehsan.

Yousofshahi, Mona.

Nair, Nikhil U.

Hassoun, Soha.


  • Directed evolution of enzymes consists of an iterative process of creating mutant libraries and choosing desired phenotypes through screening or selection until the enzymatic activity reaches a desired goal. The biggest challenge in directed enzyme evolution is identifying high-throughput screens or selections to isolate the variant(s) with the desired property. We present in this paper a computational ... read more
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  • Hassanpour, Neda, Ehsan Ullah, Mona Yousofshahi, Nikhil U. Nair, and Soha Hassoun. "Selection Finder (SelFi): A Computational Metabolic Engineering Tool to Enable Directed Evolution of Enzymes." Metabolic Engineering Communications 4 (June 2017): 37-47. doi:10.1016/j.meteno.2017.02.003.
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