Association of IL-1B gene polymorphism with IL-1β levels in gingival crevicular fluid (GCF) and bacterial profile in patients with periodontitis.

Pani, Pinelopi.


  • Abstract: Background Inflammatory cytokines, such as interleukin-1β (IL-1β), play a crucial role in the pathogenesis of periodontal diseases. A high individual variation in the levels of IL-1β in gingival crevicular fluid (GCF) has been previously reported in patients with periodontitis that may affect the periodontal outcome. GCF IL-1β levels are possibly affected by genetic polymorphisms and/or ... read more
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