Investigation into the Role of Smooth Muscle Notch in Atherosclerosis.

Davis-Knowlton, Jessica.


  • Vascular occlusive diseases underlie ischemic heart disease and stroke, the leading causes of death worldwide. We are interested in vascular smooth muscle cells (SMC) during atherogenesis, as they contribute to plaque formation and may determine susceptibility to rupture. Notch signaling is implicated in vascular disease progression, and we previously identified a Notch receptor-specific ... read more
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