High Throughput Screening of Potential Neuroprotective Compounds Using a Herpes-Induced Brain Model of Sporadic Alzheimer's Disease

Silveira, Isabella A.


  • Here, we describe a screening of a number of notable neuroprotective compounds with links to neurodegenerative disorders using a herpes-induced AD brain model previously published by the Kaplan Lab. We report successful reductions in Aβ plaque-like formation in five compounds: metformin, resveratrol, curcumin, green tea catechins, and citicoline. Impact of the compounds on neuronal function and ... read more
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