Modeling Human MEGF10 Myopathy in Drosophila melanogaster.

Matin, Bahar.

2015

Description
  • Abstract: MEGF10 myopathy or EMARDD (Early onset of Myopathy, Areflexia, Reparatory Distress and Dysphagia) is a rare human congenital muscle disease caused by mutations in MEGF10. This single transmembrane receptor is expressed in skeletal muscles, the retina and in CNS glial cells, and is conserved through evolution. The Drosophila melanogaster (i.e. fruit fly) homolog of human MEGF10 is Drpr. C... read more
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