CRF1 Receptor Antagonist Injections Increase Medial Prefrontal Cortex Serotonin after Alcohol Self-Administration

Carlson, Julia M.


  • Aggressive behaviors comorbid with alcohol abuse are a public health crisis. These behaviors are historically correlated to an inverse concentration of serotonin in the central nervous system. Corticotropin-Releasing Factor (CRF) antagonists that mediate the physiological stress response have recently begun to be developed to treat alcohol abuse. As CRF modulates serotonergic release, it may affect ... read more
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