CRF1 Receptor Antagonist Injections Increase Medial Prefrontal Cortex Serotonin after Alcohol Self-Administration

Carlson, Julia M.

2011

Description
  • Aggressive behaviors comorbid with alcohol abuse are a public health crisis. These behaviors are historically correlated to an inverse concentration of serotonin in the central nervous system. Corticotropin-Releasing Factor (CRF) antagonists that mediate the physiological stress response have recently begun to be developed to treat alcohol abuse. As CRF modulates serotonergic release, it may affec... read more
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