The Role of Aconitase in the Regulation of Metabolism and Sporulation in Bacillus subtilis.

Pechter, Kieran.


  • Abstract: Previously, it was shown that an aconitase (citB) null mutation results in a vast over-accumulation of citrate in the culture supernatant of growing Bacillus subtilis cells, a phenotype that causes secondary effects, including the hyper-expression of the citB promoter. The first chapter of this thesis, in part, reveals the mechanism of this hyper- expression: CcpC, which acts as a r... read more
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