Associations of the FTO rs9939609 and the MC4R rs17782313 polymorphisms with type 2 diabetes are modulated by diet, being higher when adherence to the Mediterranean diet pattern is low.

Ortega-Azorín, Carolina.

Sorlí, Jose V.

Asensio, Eva M.

Coltell, Oscar.

Martínez-González, Miguel Ángel.

Salas-Salvadó, Jordi.

Covas, Maria-Isabel.

Arós, Fernando.

Lapetra, José.

Serra-Majem, Lluís.

Gómez-Gracia, Enrique.

Fiol, Miquel.

Sáez-Tormo, Guillermo.

Pintó, Xavier.

Muñoz, Miguel Angel.

Ros, Emilio.

Ordovás, Jose M.

Estruch, Ramon.

Corella, Dolores.

2012

Description
  • Background: Although the Fat Mass and Obesity (FTO) and Melanocortin-4 Receptor (MC4R) genes have been consistently associated with obesity risk, the association between the obesity-risk alleles with type 2 diabetes is still controversial. In some recent meta-analyses in which significant results have been reported, the associations ... read more
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  • Ortega-Azorín, Carolina, Jose V. Sorlí, Eva M. Asensio, Oscar Coltell, Miguel Ángel Martínez-González, Jordi Salas-Salvadó, Maria-Isabel Covas, Fernando Arós, José Lapetra, Lluís Serra-Majem, Enrique Gómez-Gracia, Miquel Fiol, Guillermo Sáez-Tormo, Xavier Pintó, Miguel Angel Muñoz, Emilio Ros, Jose M. Ordovás, Ramon Estruch, and Dolores Corella. "Associations of the FTO rs9939609 and the MC4R rs17782313 polymorphisms with type 2 diabetes are modulated by diet, being higher when adherence to the Mediterranean diet pattern is low." Cardiovascular Diabetology 11, no. 1 (12, 2012): 1-12.
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