Identification of factors that modulate Yop translocation during animal and tissue culture infection of Yersinia pseudotuberculosis.

Keith, Julia.


  • Abstract: The gram-negative pathogen, Yersinia pseudotuberculosis evades the host immune system by injecting effector proteins (Yops) into host cells through its type III secretion system. These effector proteins disarm host defenses and allow the bacteria to establish infection. Both host and bacterial factors modulate Yop translocation. Bacterial growth during animal infection is controlled by n... read more
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