Design of Stapled Peptide Ligands of GABARAP to Inhibit Autophagy

Brown, Hawley F.


  • Autophagy is a process in which cells recycle damaged or unnecessary proteins and organelles to use for maintenance and growth. This process is important for cellular health, but when dysregulated, it is implicated in many diseases. For example, in some aggressive, late-stage cancers, cells become “autophagy addicted,” and rely heavily on autophagy as a housekeeping process and to provide the ... read more
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