mGluR5 functionally interacts with estrogen receptors and is required in the female ventromedial hypothalamus for the regulation of glucose and lipid homeostasis

Panessiti, Micaella.


  • Abstract: The metabolic syndrome, characterized by dysregulated glycemic control and lipid metabolism, disproportionately affects postmenopausal women and is a major public health concern. The central mechanisms governing peripheral glucose and lipid homeostasis and the role of estrogens in these systems are poorly understood. Previous investigations demonstrated that brain-derived neurotrophic ... read more
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