Investigations on the lgx-1 gene in Caenorhabditis elegans.

Yen, Lawrence L.


  • Lymphatic filariasis affects around 120 million people world wide (WHO), and is caused by nematodes Brugia malayi, Brugia timori, and Wuchereria bancrofti in many developing countries (Duke, 2001). The chitin synthesis and processing pathway may serve as a potential drug target for filariasis as the nematodes that cause the disease produce chitin while vertebrates do not. The model organism chosen... read more
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