Tumor progression locus 2 ablation suppressed hepatocellular carcinoma development by inhibiting hepatic inflammation and steatosis in mice.

Li, Xinli.

Liu, Chun.

Ip, Blanche C.

Hu, Kang-Quan.

Smith, Donald E.

Greenberg, Andrew S.

Wang, Xiang-Dong.

2015

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  • Background: Tumor progression locus 2 (TPL2), a serine-threonine kinase, functions as a critical regulator of inflammatory pathways and mediates oncogenic events. The potential role of Tpl2 in nonalcoholic fatty liver disease (NAFLD) associated hepatocellular carcinoma (HCC) development remains unknown.

    Keywords: TPL2, HCC, ... read more
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  • Li, Xinli, Chun Liu, Blanche C. Ip, Kang-Quan Hu, Donald E. Smith, Andrew S. Greenberg, and Xiang-Dong Wang. "Tumor progression locus 2 ablation suppressed hepatocellular carcinoma development by inhibiting hepatic inflammation and steatosis in mice." Journal of Experimental & Clinical Cancer Research 34, no. 1 (12, 2015): 1-8.
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vq280096f
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