Optogenetic Regulation of intracellular cyclic adenosine monophosphate and glucose-stimulated insulin secretion in pancreatic beta cells.

Zhang, Fan.


  • Diabetes affects millions of people worldwide. Islet or whole pancreas transplantation is a promising method for the treatment of Type I diabetes (T1D), which results from autoimmune damage or dysfunction of pancreatic beta cells, which producing insulin. While transplantation is limited by the shortage of healthy donor tissues, cell therapy is a promising modality for the treatment or even ... read more
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