The Role of Intestinal Microbiota in the Pathogenesis of Spondyloarthritis

Haley, Emma K.


  • Background: Spondyloarthritis (SpA) is a family of inflammatory rheumatic diseases that variably target the spine, joints, skin and intestine. Overexpression of IL-23 by means of hydrodynamic tail vein injection of IL-23 minicircles (EEV) into adult mice results in a SpA-like disease. The impact of microbiota on inflammatory diseases including SpA has gained much attention over the last few ... read more
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