%0 PDF %T Genetic defects of GDF6 in the zebrafish out of sight mutant and in human eye developmental anomalies. %A den Hollander, Anneke I.; Biyanwila, Janisha.; Kovach, Peter.; Bardakjian, Tanya.; Traboulsi, Elias I.; Ragge, Nicola K.; Schneider, Adele.; Malicki, Jarema. %D 2016-08-12T18:03:25.936Z %8 2016-08-12 %R http://localhost/files/v405sn940 %X Background: The size of the vertebrate eye and the retina is likely to be controlled at several stages of embryogenesis by mechanisms that affect cell cycle length as well as cell survival. A mutation in the zebrafish out of sight (out) locus results in a particularly severe reduction of eye size. The goal of this study is to characterize the out m233mutant, and to determine whether mutations in the out gene cause microphthalmia in humans.; Springer Open. %[ 2018-10-11 %9 Text %~ Tufts Digital Library %W Institution