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Abstract: Polybrominated diphenyl ethers (PBDEs) are synthetic brominated flame retardants used in plastics and textiles in a wide array of consumer products. These compounds volatilize from consumer products, are toxic at low concentrations, persist in the environment and bioaccumulate in wildlife and humans. PBDEs are ubiquitous in the global natural environment and have been detected in various... read morehuman tissues. For this thesis, I conducted a human health risk assessment to evaluate potential risks to the general population posed by PBDEs measured in the Massachusetts environment. Using data from studies reporting PBDE levels in Massachusetts and elsewhere in the U.S., I employed a deterministic risk model to calculate estimated risks and then compared the risks to limits used by MassDEP and USEPA. The results of this risk assessment suggest that children from birth to eleven years of age may experience potentially significant non-cancer health risks from exposures to PDBEs. This is of concern because the non-cancer risks are largely driven by exposure to congeners that have Reference Doses based on adverse developmental neurological effects. Given that the brain and other parts of the neurological system are still developing during infancy and early childhood, young children are likely the most sensitive population for these critical effects. Thus, the segment of the population that is likely experiencing the highest level of exposure to PBDEs is also the most vulnerable to its critical effects. The major findings of this study are similar to recent PBDE exposure studies conducted elsewhere in the U.S.
Thesis (M.S.)--Tufts University, 2011.
Submitted to the Dept. of Civil Engineering.
Advisor: Anne Marie Desmarais.
Committee: David Gute, and Carol Rowan-West.
Keywords: Environmental Health, and Environmental Engineering.read less
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