Phosphorylated ADAP promotes integrin-independent adhesion by stabilizing T cell receptor-induced SLP-76 microclusters.

Lewis, Juliana.

2012

Description
  • Abstract: T cell activation occurs in the context of the immune synapse, a specialized adhesive junction that forms at the interface between T cells and antigen presenting cells. Signaling complexes that contain the SLP-76 adaptor protein form alongside the TCR at the immune synapse and effectively augment stable T cell contacts by activating integrins. These SLP-76 microclusters also bridge enzym... read more
This object is in collection Corporate name Permanent URL
ID:
tm70n681h
To Cite:
DCA Citation Guide    EndNote