Determining the role of PI3K-β and PI3K-δ in Canine Hemangiosarcoma and Human Angiosarcoma.

Gutwillig, Megan.


  • Neoplastic disease arising from endothelial cells occurs spontaneously in humans (angiosarcoma, AS) and pet dogs (hemangiosarcoma, HSA) and in both species exhibits aggressive biologic behavior including early metastasis and chemotherapy resistance. While AS is a rare cancer, with 300-500 new diagnoses per year, HSA is far more common, affecting over 50,000 pet dogs yearly. Molecular and ... read more
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