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Abstract: Calcific aortic valve disease (CAVD) affects 2-3% of the population
age over the age of 75 years. Surgical replacement remains the only treatment for CAVD,
highlighting an acute need to better understand CAVD biology to develop medical treatments.
The pathological process of CAVD shares phenotypic and transcriptional similarities with
the physiological process of osteogenesis. Since ... read more