LRP1 endocytosis is regulated by KIF13B through the interaction with hDLG1

Mills, Joslyn.


  • Abstract: KIF13B, a kinesin-3 family motor, was originally identified by virtue of its biochemical interaction with human homolog of Drosophila discs large tumor suppressor (hDLG1). Unlike its homolog KIF13A, the KIF13B contains a carboxyl-terminal CAP-Gly domain. To investigate the specific functional role of the CAP-Gly domain in KIF13B, and its possible compensation by KIF13A, we developed ... read more
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