| Description |
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Abstract: Tendon and ligaments have poor healing capacity and when
injured often require surgical intervention. Tissue replacement via autografts and
allografts are non-ideal strategies that can lead to future problems. As an
alternative, scaffold-based tissue engineering strategies are being pursued. In this
review, we describe design ... read moreconsiderations and major recent advancements of scaffolds
for tendon/ligament engineering. Specifically, we outline native tendon/ligament
characteristics critical for design parameters and outcome measures, and introduce
synthetic and naturally-derived biomaterials used in tendon/ligament scaffolds. We
will describe applications of these biomaterials in advanced tendon/ligament
engineering strategies including the utility of scaffold functionalization, cyclic
strain, growth factors, and interface considerations. The goal of this review is to
compile and interpret the important findings of recent tendon/ligament engineering
research in an effort towards the advancement of regenerative
strategies.
Springer Open.read less
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| Citation |
- Kuo, Catherine, Joseph E. Marturano, and Rocky S. Tuan. "Novel
strategies in tendon and ligament tissue engineering: Advanced biomaterials and
regeneration motifs." Sports Medicine, Arthroscopy, Rehabilitation, Therapy &
Technology 2, no. 1 (12, 2010): 1-14.
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