Clinical, Radiographic and Histological Comparison of Healing After Alveolar Ridge Preservation Using Bone Allograft with Two Different Xenogeneic Membranes, PART I: Clinical and Radiographic Evaluation.
Abstract: Aims: The purpose of this prospective randomized parallel arm study was to compare clinically and radiographically the hard and soft tissue remodeling 4-5 months following alveolar ridge preservation (ARP) in extraction sockets using two different membranes, Mucograft and Dynamatrix, in combination with bone grafting. A histological and histomorphometric analysis will be conducted to ... read morecompare the quantity and quality of the newly formed soft and hard tissue as part II of this study. Materials and methods: Twenty three patients completed the research, 11 in the Mucograft group and 12 in the Dynamatrix group. The clinical and radiographic measurements for hard and soft tissues were performed with the same stent for standardization and recorded at two different times; 1) before extraction, 2) 4-5 months after healing. The open flap technique following atraumatic extraction was used for the two types of membranes. Results: A slight increase in the gingival thickness and a decrease in the width of keratinized tissue were observed following healing. There was more bone resorption in the buccal and crestal areas in the alveolar ridge in comparison to the palatal and apical areas.. No statistically significant differences in the changes of hard and soft tissues were found between the two groups. . There was a statistically significant correlation for changes in the crestal bone width and the gingival thickness following healing with the buccal plate thickness before extraction. No deleterious effect on the clinical parameters of the adjacent teeth to one extracted was observed following healing.. Conclusions: Both xenogeneic collagen membranes combined with bone allograft can maintain soft tissues as well as minimize alveolar bone resorption in all dimensions following extraction with minimal postoperative complications. The thickness of the buccal plate is an important factor that determines the amount of change in crestal gingival thickness and bone width following ARP.
Thesis (M.S.)--Tufts University, 2013.
Submitted to the Dept. of Periodontology.
Advisors: Andreas Paraschis, and James Hanley.
Committee: Charles Hawley, Paul Stark, Rumpa Ganguly, and Qisheng Tu.
Keyword: Dentistry.read less