WNT Signaling and HBP1-Associated Functional Analysis in Uterine Leiomyoma: Potential for a Pharmacological Approach to Disease Treatment

Jiang, Rulan.


  • Abstract: Uterine Leiomyomas (UL) are the most common tumors in women of reproductive age, which leads to approximately 200,000 hysterectomies annually in the United States. Although over 95% of UL tumors are benign, they destroy the function of the uterus and cause abnormal uterine bleeding, anemia, pelvic pain, and recurrent pregnancy loss. Activation of the WNT pathway is well established ... read more
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