Escalated cocaine self-administration and seeking in mice after repeated intermittent social stress: a corticotropin releasing factor mechanism

Han, Xiao.


  • Abstract: Social stress has been linked to drug use disorders in humans. This dissertation employs mouse models to examine how social defeat stress influences cocaine self-administration and seeking. One of the hypotheses underlying stress effects on drug use disorders is the interaction between stress neuropeptide corticotropin releasing factor (CRF) and mesolimbic dopamine system. To assess this... read more
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