Inhibitory Effect of Glycosaminoglycans on Human Mast Cell Stimulation by IL-33

Gross, Amanda.


  • Glycosaminoglycans (GAGs) are linear, highly negatively charged carbohydrate chains present in connective tissues, primarily known for their functional role in connective tissue, joint lubrication and anticoagulant activity. Chondroitin sulfate (CS) and heparin (Hep) are also found in the numerous secretory granules of mast cells (MC), hematopoietic tissue immune cells involved in allergic ... read more
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