Genetically diverse mice are novel and valuable models of age-associated susceptibility to Mycobacterium tuberculosis.

Harrison, David E.

Astle, Clinton M.

Niazi, M Khalid.

Major, Samuel.

Beamer, Gillian L.

2014

Description
  • Background: Tuberculosis, the disease due to Mycobacterium tuberculosis, is an important cause of morbidity and mortality in the elderly. Use of mouse models may accelerate insight into the disease and tests of therapies since mice age thirty times faster than humans. However, the majority of TB research relies on inbred mouse strains, an... read more
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  • Harrison, David, Clinton M. Astle, M. Khalid Niazi, Samuel Major, and Gillian L. Beamer. "Genetically diverse mice are novel and valuable models of age-associated susceptibility to Mycobacterium tuberculosis." Immunity & Ageing 11, no. 1 (12, 2014): 1-7.
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s4655t341
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