Serum biomarker for diagnostic evaluation of pulmonary arterial hypertension in systemic sclerosis.

Rice, Lisa M.

Mantero, Julio C.

Stratton, Eric A.

Warburton, Rod.

Roberts, Kari.

Hill, Nicholas.

Simms, Robert W.

Domsic, Robyn.

Farber, Harrison W.

Layfatis, Robert.


  • Background: Systemic sclerosis-associated pulmonary arterial hypertension (SSc-PAH) is one of the leading causes of death in SSc. Identification of a serum-based proteomic diagnostic biomarker for SSc-PAH would allow for rapid non-invasive screening and could positively impact patient survival. Identification and validation of novel proteins could potentially facilitate the identification of SSc-PAH, ... read more
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