Immunotherapeutic Effect of EGCG and DAC Treatment for Triple Negative Breast Cancer

Li, Kaiqi.


  • Abstract: Triple negative breast cancer (TNBC) is defined by lack of ER, PR or overexpression of Her2. Therefore TNBC is refractory to targeted treatments for the other classes of breast cancer. The Wnt/β-catenin signaling pathway has elevated activity in TNBC, and the Wnt repressor HBP1 is decreased in TNBC. Therefore, the Yee lab sought mechanistic treatments to induce expression of Wnt inhibito... read more
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