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Background: Epigenome-wide association studies using DNA methylation have the potential to uncover novel biomarkers and mechanisms of cardiovascular disease (CVD) risk. However, the direction of causation for these associations is not always clear, and investigations to-date have often failed to replicate at the level of individual loci.
Keywords: Body mass index, Coronary heart disease, ... read moreCholesterol, Cytosine-phosphate-guanine, Cardiovascular disease, Differentially methylated region, Epigenome-wide association study, Framingham Heart Study Offspring Cohort, Glucose, High-density lipoprotein cholesterol, Hemtopoietic stem cell, High-sensitivity C-reactive protein, Low-density lipoprotein cholesterol, Myocardial infarction, Systolic blood pressure, Pack-years of smoking, Serum triglycerides, Weighted gene correlation network analysis, Women's health initiative.
Springer Open.read less
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