Abstract: Coherent
Hemodynamics Spectroscopy (CHS) is a novel technique based on quantitative relationships
between cerebral hemodynamic oscillations and relevant physiological parameters like
cerebral blood volume (CBV), cerebral blood flow (CBF), and metabolic rate of oxygen
(CMRO2). A crucial aspect for the optimal application of CHS is the implementation of
pertinent experimental protocols, ... read morewith the focus being on eliciting Coherent cerebral
hemodynamic oscillations. This work focusses on modifications implemented on existing
CHS protocols, to uncover optimal Pneumatic-Cuff based experimental conditions. Results
of this study involved examining features of the oscillations suitable for CHS, like the
Phase Synchronization Index (PSI), which serves as a measure of coherence. It was found
that certain Pneumatic-Cuff pressures and positions elicited optimally Coherent cerebral
hemodynamic oscillations compared to others. A statistical test was applied to further
check the significance of obtained results.
