Facile fabrication of stimuli responsive opal structured hydrogel arrays in a 96 well plate format.
Menon, Nandita.
2020
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Analytical sensing technologies are important in a wide range of industries such as food and biochemical and pharmaceutical industries with an overwhelming need for bench top or handheld devices that can report high throughput readings. Currently used methods incorporate complex optical and electronic detection systems which entail the use of expensive equipment for sensing. Recently, stimuli ... read moreresponsive opal hydrogels which exhibit diffraction induced color changes have been explored for their unique properties that enable simple sensing through detection using juts the naked eye. However, techniques to synthesize these hydrogels suffer from long opal deposition times, expensive steps and a lack of a standardized scalable format. This thesis explores a simple, scalable, inexpensive, and standardized fabrication procedure of hydrogel films containing opal structures. Specifically, the procedure follows a 2-step process of opal deposition on a 96 well industry standard plate used as a substrate followed by crosslinking into polymeric hydrogels. Initial results from experiments suggest that the evaporation induced method of opal deposition produces highly intense and uniform opalescent colors and reduces deposition times to 30-45 minutes.
3-minute talk presented at the Tufts Graduate Student Council's 24th Graduate Student Research Symposium, March 6, 2020.read less - Menon, Nandita. "Facile fabrication of stimuli responsive opal structured hydrogel arrays in a 96 well plate format." Presentation at the 24th Graduate Research Symposium, Tufts University, March 6, 2020.
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