Defining a microRNA-mRNA targetome for calcineurin inhibitor induced nephrotoxicity.

Benway, Christopher.

2017

Description
  • Abstract: The use of calcineurin inhibitors has revolutionized solid organ transplantation increasing survival rates dramatically. However, calcineurin inhibitor induced nephrotoxicity severely limits the use of this class of drugs in transplantation and other diseases. Here we set out to define a microRNA (miRNA)-messenger RNA (mRNA) interaction map to identify the role of miRNAs in cyclospor... read more
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