Lipidation of W-peptide to Develop Anti-Inflammatory Therapeutics.

Rodenstein, Marissa.

2015

Description
  • The W-peptide (WKYMVM-NH2/WKYMVmNH2) is a hexapeptide agonist of the formyl peptide receptor (FPR) family of G-protein coupled receptors (GPCRs) that act as checkpoints in host defense and can thus be exploited for anti-inflammatory drugs. Discovered through a hexapeptide screening, WKYMVM-NH2 was determined to be a chemoattractant, acting to attract neutrophils to sites of inflammation and infect... read more
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