The Role of Central Insulin Resistance in Neuronal Synaptic Plasticity Associated with Neuropsychiatric Disorders.

Xue, Chang.


  • Abstract: Diabetes and insulin resistance have been linked to cognitive impairment, mood disorders, and increased risk of Alzheimer's Disease. The mechanisms by which type 2 diabetes influences depression and anxiety are not known, but insulin resistance is associated with increased inflammation and cytokine production in some brain regions. Furthermore, ablation of insulin receptor in catecholami... read more
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