Using Physiologically Relevant Electromechanical Stimulation to Investigate Biological Mechanisms Responsible for Cardiomyocyte Hypertrophy.

Bretherton, Ross.


  • Cardiovascular disease is the leading cause of death in US, has recently become the leading cause of death in the world as well • During a myocardial infarction (heart attack), over 25% of the heart’s cardiomyocytes (muscle cells) can die in only a few hours • Scar formation post-infarct is initially beneficial, but leads to a cascade of compensatory mechanisms that eventually lead to Heart Failure ... read more
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