Pro- and anti-inflammatory mechanisms regulating the mammalian response to Borrelia burgdorferi.

Marre, Meghan.


  • Abstract: Borrelia burgdorferi stimulates a strong inflammatory response during infection of a mammalian host. Toll-like receptors (TLRs), especially TLR2/1 heterodimers which recognize bacterial lipopeptides, play the major role in the induction of the inflammatory response to B. burgdorferi. Adaptors and co-receptors that mediate this process, as well as the mechanisms by which these adaptors an... read more
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