Epstein-Barr virus persistence: implications for the pathogenesis of endemic Burkitt's and immunosuppression-related B-cell lymphoma

Torgbor, Charles.


  • Abstract: The germinal center model (GCM) of Epstein-Barr virus (EBV) persistence proposes that EBV infects and drives naïve B cells through the GC to become resting memory B cells where the virus persists quiescently in a non-pathogenic state for the lifetime of the host. Yet, EBV causes several cancers. First, we asked how simultaneous infection with Plasmodium falciparum malaria and EBV ... read more
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