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Ternary mixtures of saturated and unsaturated lipids together with cholesterol can be induced to phase separate by photo-peroxidation into lipid-ordered (lo) and lipid-disordered (ld) domains. Because these have different mechanical properties, the phase separation is accompanied by dramatic changes in morphology. This work considers a tubule composed of ld phase with lo phase inclusions that ... read morepossess greater rigidity; this system has been shown experimentally by Yuan and coworkers to spontaneously adopt either banded or disk configurations following phase separation. The static behavior of inter-domain interactions is analyzed in each of these geometries by solving the linearized shape equations. These calculations suggest a possible mechanism by which the two structures form.read less
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