Disparities in allele frequencies and population differentiation for 101 disease-associated single nucleotide polymorphisms between Puerto Ricans and non-Hispanic whites.

Mattei, Josiemer.

Parnell, Laurence D.

Lai, Chao-Qiang.

Garcia-Bailo, Bibiana.

Adiconis, Xian.

Shen, Jian.

Arnett, Donna.

Demissie, Serkalem.

Tucker, Katherine L.

Ordovas, Jose M.

2009

Description
  • Background: Variations in gene allele frequencies can contribute to differences in the prevalence of some common complex diseases among populations. Natural selection modulates the balance in allele frequencies across populations. Population differentiation (FST) can evidence environmental selection pressures. Such genetic information is ... read more
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  • Mattei, Josiemer, Laurence D. Parnell, Chao-Qiang Lai, Bibiana Garcia-Bailo, Xian Adiconis, Jian Shen, Donna Arnett, Serkalem Demissie, Katherine L. Tucker, and Jose M. Ordovas. "Disparities in allele frequencies and population differentiation for 101 disease-associated single nucleotide polymorphisms between Puerto Ricans and non-Hispanic whites." BMC Genetics 10, no. 1 (12, 2009): 1-12.
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nv935d843
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