In vitro and quantitative phosphoproteomic modeling of castration resistant prostate cancer.

Lescarbeau, Reynald.


  • Abstract: Prostate cancer is a highly prevalent disease in elderly men, which is treatable at early stages, yet causes morbidity and death upon progression to a hormone resistant, metastatic stage. Given prostate cancer's propensity to metastasize to the bone marrow and escape from androgen deprivation, the role of the bone marrow microenvironment in enabling castration resistant growth was examin... read more
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