Silk-based Tissue Engineered Constructs to Improve Tissue Regeneration and Vascularization with Stem Cells

Wang, Yuqi.


  • Abstract: A silk-based hydrogel system was explored to evaluate the effects of substrate stiffness and cyclic stretch on human mesenchymal stem cell (hMSCs) differentiation. The hydrogel fibers were highly tunable, elastic and supported the survival and growth of encapsulated hMSCs. The hMSCs in silk hydrogel fibers at 50 kPa and 150 kPa both transferred from a multipotent stem cell state to ... read more
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