Vav1 Controls the Stability and Function of SLP-76 Containing Signaling Microclusters.

Sylvain, Nicholas.


  • Abstract: Generation of productive immune responses requires T cell activation and differentiation into various effector and helper subsets. T cell activation is mediated by signaling events that originate at the T cell receptor (TCR) and result in the phosphorylation of several critical adapter and effector molecules. These early signaling events result in the formation of multisubunit structures... read more
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